I haven't kept up with it, but I used to find that a combination of 'adblock plus' and 'noscript' was able to keep things under control - to a point. But would sometimes require some manual intervention.
I use uBlock Origin, a Firefox extension, since it is easy on the CPU and memory. It is not an adblocker, but actually a content blocker with lots of ways of customizing what you want to filter. It works much better in my opinion.